Curodont Repair

Guided Enamel Regeneration of early carious lesions
CurodontTM Repair is the first biomimetic system to treat early caries by regenerating enamel. CurodontTM Repair offers an easy, pain-free and conservative solution to patients of all ages.

Its revolutionary Monomer-Peptide 104 technology is based on a simple peptide, made of naturally occurring amino acids. On application by dentists or dental hygienists*, it diffuses into the depth of early carious lesions within 5 minutes and self-assembles into a biomatrix, similar to the natural enamel matrix. The biomatrix then attracts calcium and phosphate ions from saliva to form hydroxyapatite, thus enabling Guided Enamel Regeneration within the lesion.

Clinical trials have proven that the patented peptide technology enables significantly greater caries regression and inactivation than the current gold standard fluoride varnish alone, with a demonstrated success rate of 86-100% (vs about 35% for fluoride varnishes).1,2

In German-speaking countries alone, CurodontTM Repair has been used to treat over 60,000 carious lesions in the last decade.

1. Alkilzy M, et al. Self-assembling Peptide P11-4 and Fluoride for Regenerating Enamel. J Dent Res. 2018;97:148-154.

2. Doberdoli D. et al. Randomized Clinical Trial investigating Self-Assembling Peptide P11-4 for Treatment of Early Occlusal Caries. Sci Rep. 2020;10:4195

* Under dentist direction.